| http://purl.uniprot.org/citations/26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26361887 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcriptional co-activator BOB.1/OBF.1 is crucial for Octamer-driven transcription in B cells. BOB.1/OBF.1-deficiency leads to tremendous defects in B-cell development and function. Therefore, in the past research focused on the identification of BOB.1/OBF.1 target genes. However, the regulation of BOB.1/OBF.1 expression itself is poorly understood. Here we show that in B cells NF-κB as well as to some extent NFAT proteins are involved in the activation of basal as well as inducible BOB.1/OBF.1 expression by direct binding to the BOB.1/OBF.1 promoter. Moreover, the analysis of different inducers of NF-κB, like several TLR ligands, TNF-α, BAFF, or LTα1β2, revealed that both the canonical and noncanonical NF-κB pathways are involved in the induction of BOB.1/OBF.1 gene. The identification of so far unknown inducers that regulate BOB.1/OBF.1 expression in B cells provides novel insights in the potential function of BOB.1/OBF.1 during different aspects of B-cell development and function."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.201545475"xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Quandt J."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Brunner C."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Wirth T."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Weihrich P."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Kilzheimer M."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/author | "Langhans J."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/name | "Eur J Immunol"xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/pages | "3441-3453"xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/title | "NF-kappaB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells."xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://purl.uniprot.org/core/volume | "45"xsd:string |
| http://purl.uniprot.org/citations/26361887 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26361887 |
| http://purl.uniprot.org/citations/26361887 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JGK6-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_Q0PM15-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_Q0PM16-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A1L1SRM5-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A1S5WLE4-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A4L9Q2-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A494B901-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A494BA44-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |
| http://purl.uniprot.org/uniprot/#_A0A1S5WLF0-mappedCitation-26361887 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26361887 |