RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26371314http://www.w3.org/2000/01/rdf-schema#comment"B cells respond to antigens by engagement of their B-cell antigen receptor (BCR) and of coreceptors through which signals from helper T cells or pathogen-associated molecular patterns are delivered. We show that the proliferative response of B cells to the latter stimuli is controlled by BCR-dependent activation of phosphoinositidyl 3-kinase (PI-3K) signaling. Glycogen synthase kinase 3β and Foxo1 are two PI-3K-regulated targets that play important roles, but to different extents, depending on the specific mitogen. These results suggest a model for integrating signals from the innate and the adaptive immune systems in the control of the B-cell immune response."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1516428112"xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Waisman A."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Franklin A."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Rajewsky K."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Otipoby K.L."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Srinivasan L."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/author"Derudder E."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/name"Proc Natl Acad Sci U S A"xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/pages"12145-12150"xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/title"The B-cell antigen receptor integrates adaptive and innate immune signals."xsd:string
http://purl.uniprot.org/citations/26371314http://purl.uniprot.org/core/volume"112"xsd:string
http://purl.uniprot.org/citations/26371314http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26371314
http://purl.uniprot.org/citations/26371314http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26371314
http://purl.uniprot.org/uniprot/#_A0A1Y7VLC4-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_A0A1Y7VLX7-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_A0A1Y7VIP5-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_A0A1Y7VP77-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_E9Q5D6-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_P01808-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/#_P69566-mappedCitation-26371314http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/A0A1Y7VLX7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26371314
http://purl.uniprot.org/uniprot/A0A1Y7VP77http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26371314