| http://purl.uniprot.org/citations/26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26376423 | http://www.w3.org/2000/01/rdf-schema#comment | "Mitochondria have retained indispensable but limited genetic information and they import both proteins and nucleic acids from the cytosol. RNA import is essential for gene expression and regulation, whereas competence for DNA uptake is likely to contribute to organellar genome dynamics and evolution. Contrary to protein import mechanisms, the way nucleic acids cross the mitochondrial membranes remains poorly understood. Using proteomic, genetic and biochemical approaches with both plant and yeast organelles, we develop here a model for DNA uptake into mitochondria. The first step includes the voltage-dependent anion channel and an outer membrane-located precursor fraction of a protein normally located in the inner membrane. To proceed, the DNA is then potentially recruited in the intermembrane space by an accessible subunit of one of the respiratory chain complexes. Final translocation through the inner membrane remains the most versatile but points to the components considered to make the mitochondrial permeability transition pore. Depending on the size, DNA and RNA cooperate or compete for mitochondrial uptake, which shows that they share import mechanisms. On the other hand, our results imply the existence of more than one route for nucleic acid translocation into mitochondria."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbamcr.2015.09.011"xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Hammann P."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Ibrahim N."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Dietrich A."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Konstantinov Y.M."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Weber-Lotfi F."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Koulintchenko M.V."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/author | "Mileshina D.V."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/pages | "3165-3181"xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/title | "Nucleic acid import into mitochondria: New insights into the translocation pathways."xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://purl.uniprot.org/core/volume | "1853"xsd:string |
| http://purl.uniprot.org/citations/26376423 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26376423 |
| http://purl.uniprot.org/citations/26376423 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26376423 |
| http://purl.uniprot.org/uniprot/#_D6W196-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P40035-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P38325-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P38127-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P39953-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P04710-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P04840-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |
| http://purl.uniprot.org/uniprot/#_P07257-mappedCitation-26376423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26376423 |