| http://purl.uniprot.org/citations/26379425 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26379425 | http://www.w3.org/2000/01/rdf-schema#comment | "The objective of this study was to investigate the anticancer efficacy of dimercaptosuccinic acid-modified iron oxide magnetic nanoparticles coloaded with anti-CD22 antibodies and doxorubicin (anti-CD22-MNPs-DOX) on non-Hodgkin's lymphoma cells. The physical properties of anti-CD22-MNPs-DOX were studied and its antitumor effect on Raji cells in vitro was evaluated using the Cell Counting Kit-8 assay. Furthermore, cell apoptosis and intracellular accumulation of doxorubicin were determined by flow cytometry. The results revealed that anti-CD22-MNPs-DOX inhibited the proliferation of Raji cells, significantly increased the uptake of doxorubicin, and induced apoptosis. Therefore, it was concluded that a coloaded antibody and chemotherapeutic drug with magnetic nanoparticles might be an efficient targeted treatment strategy for non-Hodgkin's lymphoma."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.org/dc/terms/identifier | "doi:10.2147/dddt.s86764"xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Fang Y."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Lu Q."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Song L."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Sun M."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/author | "Xia G."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/name | "Drug Des Devel Ther"xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/pages | "5123-5133"xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/title | "Novel synthesizing method of pH-dependent doxorubicin-loaded anti-CD22-labelled drug delivery nanosystem."xsd:string |
| http://purl.uniprot.org/citations/26379425 | http://purl.uniprot.org/core/volume | "9"xsd:string |
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| http://purl.uniprot.org/citations/26379425 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26379425 |
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