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http://purl.uniprot.org/citations/26387718http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26387718http://www.w3.org/2000/01/rdf-schema#comment"In the neocortex, higher-order areas are essential to integrate sensory-motor information and have expanded in size during evolution. How higher-order areas are specified, however, remains largely unknown. Here, we show that the migration and distribution of early-born neurons, the Cajal-Retzius cells (CRs), controls the size of higher-order areas in the mouse somatosensory, auditory, and visual cortex. Using live imaging, genetics, and in silico modeling, we show that subtype-specific differences in the onset, speed, and directionality of CR migration determine their differential invasion of the developing cortical surface. CR migration speed is cell autonomously modulated by vesicle-associated membrane protein 3 (VAMP3), a classically non-neuronal mediator of endosomal recycling. Increasing CR migration speed alters their distribution in the developing cerebral cortex and leads to an expansion of postnatal higher-order areas and congruent rewiring of thalamo-cortical input. Our findings thus identify novel roles for neuronal migration and VAMP3-dependent vesicular trafficking in cortical wiring."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.org/dc/terms/identifier"doi:10.1016/j.cub.2015.08.028"xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Arai Y."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Morishita Y."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Galli T."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Proux-Gillardeaux V."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Tissir F."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Pierani A."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Causeret F."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Borello U."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Barber M."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Jabaudon D."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Govindan S."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Coppola E."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Pfrieger F.W."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Vigier L."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Contremoulins V."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/author"Ledonne F."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/name"Curr Biol"xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/pages"2466-2478"xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/title"Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas."xsd:string
http://purl.uniprot.org/citations/26387718http://purl.uniprot.org/core/volume"25"xsd:string
http://purl.uniprot.org/citations/26387718http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26387718