http://purl.uniprot.org/citations/26387718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26387718 | http://www.w3.org/2000/01/rdf-schema#comment | "In the neocortex, higher-order areas are essential to integrate sensory-motor information and have expanded in size during evolution. How higher-order areas are specified, however, remains largely unknown. Here, we show that the migration and distribution of early-born neurons, the Cajal-Retzius cells (CRs), controls the size of higher-order areas in the mouse somatosensory, auditory, and visual cortex. Using live imaging, genetics, and in silico modeling, we show that subtype-specific differences in the onset, speed, and directionality of CR migration determine their differential invasion of the developing cortical surface. CR migration speed is cell autonomously modulated by vesicle-associated membrane protein 3 (VAMP3), a classically non-neuronal mediator of endosomal recycling. Increasing CR migration speed alters their distribution in the developing cerebral cortex and leads to an expansion of postnatal higher-order areas and congruent rewiring of thalamo-cortical input. Our findings thus identify novel roles for neuronal migration and VAMP3-dependent vesicular trafficking in cortical wiring."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cub.2015.08.028"xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Arai Y."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Morishita Y."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Galli T."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Proux-Gillardeaux V."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Tissir F."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Pierani A."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Causeret F."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Borello U."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Barber M."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Jabaudon D."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Govindan S."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Coppola E."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Pfrieger F.W."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Vigier L."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Contremoulins V."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/author | "Ledonne F."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/name | "Curr Biol"xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/pages | "2466-2478"xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/title | "Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas."xsd:string |
http://purl.uniprot.org/citations/26387718 | http://purl.uniprot.org/core/volume | "25"xsd:string |
http://purl.uniprot.org/citations/26387718 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26387718 |