| http://purl.uniprot.org/citations/26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26440898 | http://www.w3.org/2000/01/rdf-schema#comment | "Also known as Sqstm1, p62 is a selective autophagy adaptor with a ubiquitin-binding domain. However, the role of p62 in the host defense against Toxoplasma gondii infection is unclear. Here, we show that interferon γ (IFN-γ) stimulates ubiquitin and p62 recruitment to T. gondii parasitophorous vacuoles (PVs). Some essential autophagy-related proteins, but not all, are required for this recruitment. Regardless of normal IFN-γ-induced T. gondii clearance activity and ubiquitination, p62 deficiency in antigen-presenting cells (APCs) and mice diminishes the robust IFN-γ-primed activation of CD8(+) T cells that recognize the T. gondii-derived antigen secreted into PVs. Because the expression of Atg3 and Irgm1/m3 in APCs is essential for PV disruption, ubiquitin and p62 recruitment, and vacuolar-antigen-specific CD8(+) T cell activation, IFN-γ-mediated ubiquitination and the subsequent recruitment of p62 to T. gondii are specifically required for the acquired immune response after PV disruption by IFN-γ-inducible GTPases."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.celrep.2015.09.005"xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Bando H."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Lee Y."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Sakaguchi N."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Yamamoto M."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Saitoh T."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Akira S."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Sasai M."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Ma J.S."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/author | "Ohshima J."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/name | "Cell Rep"xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/pages | "223-233"xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/title | "p62 Plays a Specific Role in Interferon-gamma-Induced Presentation of a Toxoplasma Vacuolar Antigen."xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/26440898 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26440898 |
| http://purl.uniprot.org/citations/26440898 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26440898 |
| http://purl.uniprot.org/uniprot/#_E9Q9N8-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |
| http://purl.uniprot.org/uniprot/#_A0A385JBX3-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |
| http://purl.uniprot.org/uniprot/#_J7NUP1-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |
| http://purl.uniprot.org/uniprot/#_D3YZJ1-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |
| http://purl.uniprot.org/uniprot/#_F6VD69-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |
| http://purl.uniprot.org/uniprot/#_E9PW35-mappedCitation-26440898 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26440898 |