RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/26447473http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26447473http://www.w3.org/2000/01/rdf-schema#comment"Emp46p and Emp47p are yeast putative cargo receptors that recycle between the endoplasmic reticulum and the Golgi apparatus. These receptors can form complexes in a pH-dependent manner, but their molecular mechanisms remain unclear. Here, we successfully reproduced their interactions in vitro solely with their coiled-coil segments, which form stable heterotetramers in the neutral condition but segregate at lower pH. Mutational data identified a key glutamate residue of Emp46p that serves as the pH-sensing switch of their oligomer formation. Our findings elucidate the mechanisms of the dynamic cargo receptor interactions in the secretory pathway and the design framework of the environment-responsive molecular assembly and disassembly systems."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0140287"xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Ishii K."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Kato K."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Kobayashi Y."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Kim A."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Sato K."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Uchiyama S."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Noda M."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Nakano A."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Yagi H."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Kurimoto E."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Kajino M."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/author"Enda H."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/pages"e0140287"xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/title"pH-Dependent Assembly and Segregation of the Coiled-Coil Segments of Yeast Putative Cargo Receptors Emp46p and Emp47p."xsd:string
http://purl.uniprot.org/citations/26447473http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/26447473http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26447473
http://purl.uniprot.org/citations/26447473http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26447473
http://purl.uniprot.org/uniprot/#_A0A8H4BX37-mappedCitation-26447473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26447473
http://purl.uniprot.org/uniprot/#_A0A6A5PXS7-mappedCitation-26447473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26447473
http://purl.uniprot.org/uniprot/#_P43555-mappedCitation-26447473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26447473