http://purl.uniprot.org/citations/26447473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26447473 | http://www.w3.org/2000/01/rdf-schema#comment | "Emp46p and Emp47p are yeast putative cargo receptors that recycle between the endoplasmic reticulum and the Golgi apparatus. These receptors can form complexes in a pH-dependent manner, but their molecular mechanisms remain unclear. Here, we successfully reproduced their interactions in vitro solely with their coiled-coil segments, which form stable heterotetramers in the neutral condition but segregate at lower pH. Mutational data identified a key glutamate residue of Emp46p that serves as the pH-sensing switch of their oligomer formation. Our findings elucidate the mechanisms of the dynamic cargo receptor interactions in the secretory pathway and the design framework of the environment-responsive molecular assembly and disassembly systems."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0140287"xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Ishii K."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Kobayashi Y."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Kim A."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Sato K."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Uchiyama S."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Noda M."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Nakano A."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Yagi H."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Kurimoto E."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Kajino M."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/author | "Enda H."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/pages | "e0140287"xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/title | "pH-Dependent Assembly and Segregation of the Coiled-Coil Segments of Yeast Putative Cargo Receptors Emp46p and Emp47p."xsd:string |
http://purl.uniprot.org/citations/26447473 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/26447473 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26447473 |
http://purl.uniprot.org/citations/26447473 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26447473 |
http://purl.uniprot.org/uniprot/#_A0A8H4BX37-mappedCitation-26447473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26447473 |
http://purl.uniprot.org/uniprot/#_A0A6A5PXS7-mappedCitation-26447473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26447473 |
http://purl.uniprot.org/uniprot/#_P43555-mappedCitation-26447473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26447473 |