| http://purl.uniprot.org/citations/26455799 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26455799 | http://www.w3.org/2000/01/rdf-schema#comment | "Cilia are small antenna-like cellular protrusions critical for many developmental signaling pathways. The ciliary protein Arl3 has been shown to act as a specific release factor for myristoylated and farnesylated ciliary cargo molecules by binding to the effectors Unc119 and PDE6δ. Here we describe a newly identified Arl3 binding partner, CCDC104/CFAP36. Biochemical and structural analyses reveal that the protein contains a BART-like domain and is called BARTL1. It recognizes an LLxILxxL motif at the N-terminal amphipathic helix of Arl3, which is crucial for the interaction with the BART-like domain but also for the ciliary localization of Arl3 itself. These results seem to suggest a ciliary role of BARTL1, and possibly link it to the Arl3 transport network. We thus speculate on a regulatory mechanism whereby BARTL1 aids the presentation of active Arl3 to its GTPase-activating protein RP2 or hinders Arl3 membrane binding in the area of the transition zone."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2015.08.016"xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Boldt K."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Wittinghofer A."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Koerner C."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Roepman R."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Horn N."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Ueffing M."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "van Reeuwijk J."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "van Beersum S.E."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Lange S.M."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Kosling S.K."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/author | "Lokaj M."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/pages | "2122-2132"xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/title | "The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function."xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/26455799 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26455799 |
| http://purl.uniprot.org/citations/26455799 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26455799 |
| http://purl.uniprot.org/uniprot/Q9WUL7#attribution-F0CC43546BB1BEFE033FCDB28209970D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/26455799 |
| http://purl.uniprot.org/uniprot/Q9D0J4#attribution-F0CC43546BB1BEFE033FCDB28209970D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/26455799 |
| http://purl.uniprot.org/uniprot/Q8C6E0#attribution-F0CC43546BB1BEFE033FCDB28209970D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/26455799 |
| http://purl.uniprot.org/uniprot/Q96G28#attribution-F0CC43546BB1BEFE033FCDB28209970D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/26455799 |