http://purl.uniprot.org/citations/26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26477563 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcriptional imbalance due to the difference in the number of X chromosomes between male and female mammals is remedied through X-chromosome inactivation, the epigenetic transcriptional silencing of one of the two X chromosomes in females. The X-linked Xist long non-coding RNA functions as an X inactivation master regulator; Xist is selectively upregulated from the prospective inactive X chromosome and is required in cis for X inactivation. Here we discover an Xist antisense long non-coding RNA, XistAR (Xist Activating RNA), which is encoded within exon 1 of the mouse Xist gene and is transcribed only from the inactive X chromosome. Selective truncation of XistAR, while sparing the overlapping Xist RNA, leads to a deficiency in Xist RNA expression in cis during the initiation of X inactivation. Thus, the Xist gene carries within its coding sequence an antisense RNA that drives Xist expression."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms9564"xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Kumar S."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Kumari A."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Kalantry S."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Gayen S."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Sado T."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Harris C."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Sarkar M.K."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Buttigieg E."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Hinten M."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/author | "Maclary E."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/pages | "8564"xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/title | "An Xist-activating antisense RNA required for X-chromosome inactivation."xsd:string |
http://purl.uniprot.org/citations/26477563 | http://purl.uniprot.org/core/volume | "6"xsd:string |
http://purl.uniprot.org/citations/26477563 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26477563 |
http://purl.uniprot.org/citations/26477563 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26477563 |
http://purl.uniprot.org/uniprot/#_A0A0G2JGH3-mappedCitation-26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26477563 |
http://purl.uniprot.org/uniprot/#_A0A0G2JGR1-mappedCitation-26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26477563 |
http://purl.uniprot.org/uniprot/#_A0A0G2JED2-mappedCitation-26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26477563 |
http://purl.uniprot.org/uniprot/#_A0A0G2JF35-mappedCitation-26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26477563 |
http://purl.uniprot.org/uniprot/#_A0A0G2JF42-mappedCitation-26477563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26477563 |