http://purl.uniprot.org/citations/26488073 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26488073 | http://www.w3.org/2000/01/rdf-schema#comment | "This study was aimed to compare serum urocortin-3 (UCN3) levels in women with polycystic ovary syndrome (PCOS) and healthy women, and establish what role UCN3 levels play in PCOS. Fifty-two patients with PCOS and 55 healthy women were included in the study, matched for age and body mass index. Fasting blood glucose (FBG), insulin, hs-CRP, UCN3 and free-testosterone levels of the all participants were measured. HOMA-IR was used to calculate the insulin resistance. Circulating UCN3 levels were significantly increased in women with PCOS than in control subjects (54.49 ± 5.77 versus 51.28 ± 5.86 pmol/l, p = 0.005). Serum insulin, hs-CRP and HOMA-IR levels were higher in women with PCOS than in control group. UCN3 levels positively correlated with hs-CRP in PCOS group (r = 0.391, p = 0.004). Receiver operating characteristic (ROC) curve analysis showed that the area under the ROC curves were 0.732 (95% CI 0.634-0.830, p < 0.001) for UCN3 levels. The optimal cut-off value of UCN3 for detecting PCOS was ≥51.46 pmol/l, at which the sensitivity was 75% and specificity was 68%. Our results suggest that there is a potential link between PCOS and UCN3 levels. The results of this study support the presence of increased UCN3 levels for the association of inflammation with PCOS."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.org/dc/terms/identifier | "doi:10.3109/09513590.2015.1110135"xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Kume T."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Yilmaz O."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Calan M."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Korkmaz H.A."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Temur M."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Aksun S."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Karakulak M."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/author | "Ozun Ozbay P."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/name | "Gynecol Endocrinol"xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/pages | "218-222"xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/title | "Increased circulating urocortin-3 levels is associated with polycystic ovary syndrome."xsd:string |
http://purl.uniprot.org/citations/26488073 | http://purl.uniprot.org/core/volume | "32"xsd:string |
http://purl.uniprot.org/citations/26488073 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26488073 |
http://purl.uniprot.org/citations/26488073 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26488073 |
http://purl.uniprot.org/uniprot/#_Q969E3-mappedCitation-26488073 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26488073 |
http://purl.uniprot.org/uniprot/Q969E3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26488073 |