| http://purl.uniprot.org/citations/26495896 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26495896 | http://www.w3.org/2000/01/rdf-schema#comment | "The triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the immunoglobulin superfamily. TREM-1 has been implicated as an amplifier of inflammation. Soluble TREM-1 (sTREM-1) was investigated in different clinical conditions, but not in hemodialysis (HD) patients. We aimed to investigate sTREM-1 as a marker of inflammation in HD patients. We investigated 40 CKD patients undergoing chronic HD treatment and 15 controls. Routine laboratory investigations in addition to CRP measured by immunoturbidimetry, TNF-α, and sTREM-1 measured by ELISA were assayed in post-hemodialysis patients' blood samples and in controls' blood samples. CRP, TNF-α, and sTREM-1 levels were significantly higher in HD patients than in controls (p < 0.001 for all). sTREM-1 was positively correlated with CRP and TNF-α (r = +0.50, p < 0.001 and r = +0.53, p < 0.001 respectively). It was negatively correlated with hemoglobin concentration (r = -0.69, p < 0.001). Hemoglobin concentration was the significant predictor of sTREM-1 level (p < 0.001). In conclusion, sTREM-1 level is significantly increased in HD patients as are other pro-inflammatory markers."xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.org/dc/terms/identifier | "doi:10.1111/apm.12459"xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/author | "Essa E.S."xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/author | "Elzorkany K.M."xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/name | "APMIS"xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/pages | "969-974"xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/title | "sTREM-1 in patients with chronic kidney disease on hemodialysis."xsd:string |
| http://purl.uniprot.org/citations/26495896 | http://purl.uniprot.org/core/volume | "123"xsd:string |
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