| http://purl.uniprot.org/citations/26505415 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26505415 | http://www.w3.org/2000/01/rdf-schema#comment | "Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect. Several WNT genes are involved in craniofacial embryogenesis, and therefore may play an important role in the etiology of NSCL/P. Two SNPs (rs3809857 and rs9890413) in the WNT3 gene were subjected to case-control and case-parent analysis by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 236 unrelated patients with NSCL/P, including 128 elementary families (185 mothers and 154 fathers), and 400 control individuals from northeast China. The rs3809857 SNP, under the assumption of a dominant model, was found to induce a 2-fold lower risk of NSCL/P ORGG vs GT + TT = 0.605, 95%CI = 0.436-0.839, P = 0.003). Moreover, the family-based association test revealed an under-transmission for the minor allele T. On the other hand, we observed a significant association in the case-control and case-parent analysis of the SNP rs9890413. In addition, the P values for the haplotype of rs3809857-rs9890413 were observed to be statistically significant (P = 0.004). In conclusion, our study confirmed the association between the WNT3 variant and NSCL/P in the population tested."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.org/dc/terms/identifier | "doi:10.4238/2015.october.19.8"xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Liu Q."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Xu W."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Jiang M."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Li Z.J."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Li J.X."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Lu Y.P."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/author | "Han W.T."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/name | "Genet Mol Res"xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/pages | "12646-12653"xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/title | "Variations in WNT3 gene are associated with incidence of non-syndromic cleft lip with or without cleft palate in a northeast Chinese population."xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/26505415 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26505415 |
| http://purl.uniprot.org/citations/26505415 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26505415 |
| http://purl.uniprot.org/uniprot/#_P56703-mappedCitation-26505415 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26505415 |
| http://purl.uniprot.org/uniprot/P56703 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26505415 |