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http://purl.uniprot.org/citations/26512101http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26512101http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26512101http://www.w3.org/2000/01/rdf-schema#comment"The biogenesis of microRNAs (miRNAs), which regulate mRNA abundance through posttranscriptional silencing, comprises multiple well-orchestrated processing steps. We have identified the Arabidopsis thaliana K homology (KH) domain protein REGULATOR OF CBF GENE EXPRESSION 3 (RCF3) as a cofactor affecting miRNA biogenesis in specific plant tissues. MiRNA and miRNA-target levels were reduced in apex-enriched samples of rcf3 mutants, but not in other tissues. Mechanistically, RCF3 affects miRNA biogenesis through nuclear interactions with the phosphatases C-TERMINAL DOMAIN PHOSPHATASE-LIKE1 and 2 (CPL1 and CPL2). These interactions are essential to regulate the phosphorylation status, and thus the activity, of the double-stranded RNA binding protein and DICER-LIKE1 (DCL1) cofactor HYPONASTIC LEAVES1 (HYL1)."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1512865112"xsd:string
http://purl.uniprot.org/citations/26512101http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1512865112"xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Hagmann J."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Hagmann J."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Wang X."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Wang X."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Karlsson P."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Karlsson P."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Christie M.D."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Christie M.D."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Kulcheski F."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Kulcheski F."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Manavella P.A."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Manavella P.A."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Seymour D.K."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/author"Seymour D.K."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/26512101http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string