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http://purl.uniprot.org/citations/26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26539187http://www.w3.org/2000/01/rdf-schema#comment"Xylose utilization is one key issue for the bioconversion of lignocelluloses. It is a promising approach to engineering heterologous pathway for xylose utilization in Saccharomyces cerevisiae. Here, we constructed a xylose-fermenting yeast SyBE001 through combinatorial fine-tuning the expression of XylA and endogenous XKS1. Additional overexpression of genes RKI1, RPE1, TKL1, and TAL1 in the non-oxidative pentose phosphate pathway (PPP) in SyBE001 increased the xylose consumption rate by 1.19-fold. By repetitive adaptation, the xylose utilization rate was further increased by ∼10-fold in the resultant strain SyBE003. Gene expression analysis identified a variety of genes with significantly changed expression in the PPP, glycolysis and the tricarboxylic acid cycle in SyBE003."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.org/dc/terms/identifier"doi:10.3389/fmicb.2015.01165"xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Zhang W."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Qi X."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Zha J."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Yuan Y.J."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Li B.Z."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/author"Liu G.G."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/name"Front Microbiol"xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/pages"1165"xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/title"Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/26539187http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/26539187http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26539187
http://purl.uniprot.org/citations/26539187http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26539187
http://purl.uniprot.org/uniprot/#_P15019-mappedCitation-26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/#_P23254-mappedCitation-26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/#_P46969-mappedCitation-26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/#_Q12189-mappedCitation-26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/#_P33315-mappedCitation-26539187http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/P15019http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/Q12189http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/P23254http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26539187
http://purl.uniprot.org/uniprot/P46969http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26539187