RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26541607http://www.w3.org/2000/01/rdf-schema#comment"The sense of smell allows chemicals to be perceived as diverse scents. We used single-neuron RNA sequencing to explore the developmental mechanisms that shape this ability as nasal olfactory neurons mature in mice. Most mature neurons expressed only one of the ~1000 odorant receptor genes (Olfrs) available, and at a high level. However, many immature neurons expressed low levels of multiple Olfrs. Coexpressed Olfrs localized to overlapping zones of the nasal epithelium, suggesting regional biases, but not to single genomic loci. A single immature neuron could express Olfrs from up to seven different chromosomes. The mature state in which expression of Olfr genes is restricted to one per neuron emerges over a developmental progression that appears to be independent of neuronal activity involving sensory transduction molecules."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.org/dc/terms/identifier"doi:10.1126/science.aad2456"xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Buck L.B."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Lu Z."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Pachter L."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Trapnell C."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Qiu X."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Ye X."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Kondoh K."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Hanchate N.K."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/author"Kuang D."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/pages"1251-1255"xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/title"Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis."xsd:string
http://purl.uniprot.org/citations/26541607http://purl.uniprot.org/core/volume"350"xsd:string
http://purl.uniprot.org/citations/26541607http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26541607
http://purl.uniprot.org/citations/26541607http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26541607
http://purl.uniprot.org/uniprot/#_P0C604-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607
http://purl.uniprot.org/uniprot/#_P0C617-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607
http://purl.uniprot.org/uniprot/#_P0C623-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607
http://purl.uniprot.org/uniprot/#_P0C626-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607
http://purl.uniprot.org/uniprot/#_P0C628-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607
http://purl.uniprot.org/uniprot/#_P0C629-mappedCitation-26541607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26541607