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| http://purl.uniprot.org/citations/26545048 | http://www.w3.org/2000/01/rdf-schema#comment | "Oligodendroglioma is the quintessential molecularly-defined brain tumor. The characteristic whole-arm loss of the long arm of chromosome 1 and the short arm of chromosome 19 (1p/19q-codeletion) within the genome of these tumors facilitated the reproducible molecular identification of this subcategory of gliomas. More recently, recurrent molecular genetic alterations have been identified to occur concurrently with 1p/19q-codeletion, and definitively identify these tumors, including mutations in IDH1/2, CIC, FUBP1, and the TERT promoter, as well as the absence of ATRX and TP53 alterations. These findings provide a foundation for the consistent diagnosis of this tumor type, upon which a generation of clinical investigators have assembled a strong evidence base for the effective treatment of this disease with radiation and chemotherapy."xsd:string |
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| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/author | "Cahill D.P."xsd:string |
| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/author | "Louis D.N."xsd:string |
| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/author | "Cairncross J.G."xsd:string |
| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/name | "CNS Oncol"xsd:string |
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| http://purl.uniprot.org/citations/26545048 | http://purl.uniprot.org/core/title | "Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1."xsd:string |
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