| http://purl.uniprot.org/citations/26566124 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26566124 | http://www.w3.org/2000/01/rdf-schema#comment | "BST-2 (tetherin, CD317, HM1.24) restricts virus growth by tethering enveloped viruses to the cell surface. The role of BST-2 during influenza A virus infection (IAV) is controversial. Here, we assessed the capacity of endogenous BST-2 to restrict IAV in primary murine cells. IAV infection increased BST-2 surface expression by primary macrophages, but not alveolar epithelial cells (AEC). BST-2-deficient AEC and macrophages displayed no difference in susceptibility to IAV infection relative to wild type cells. Furthermore, BST-2 played little role in infectious IAV release from either AEC or macrophages. To examine BST-2 during IAV infection in vivo, we infected BST-2-deficient mice. No difference in weight loss or in viral loads in the lungs and/or nasal tissues were detected between BST-2-deficient and wild type animals. This study rules out a major role for endogenous BST-2 in modulating IAV in the mouse model of infection."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0142925"xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Reading P.C."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Brooks A.G."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Londrigan S.L."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Villadangos J.A."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Tate M.D."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Mintern J.D."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Purcell D.F."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Wakim L.M."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Job E.R."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Moffat J.M."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/author | "Gonelli C.A."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/pages | "e0142925"xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/title | "Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection."xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/26566124 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26566124 |
| http://purl.uniprot.org/citations/26566124 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26566124 |
| http://purl.uniprot.org/uniprot/#_Q8R2Q8-mappedCitation-26566124 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26566124 |
| http://purl.uniprot.org/uniprot/Q8R2Q8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26566124 |