| http://purl.uniprot.org/citations/26567340 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26567340 | http://www.w3.org/2000/01/rdf-schema#comment | "In response to environmental cues, the mitogen-activated protein kinase Sty1-driven signaling cascade activates hundreds of genes to induce a robust anti-stress cellular response in fission yeast. Thus, upon stress imposition Sty1 transiently accumulates in the nucleus where it up-regulates transcription through the Atf1 transcription factor. Several regulators of transcription and translation have been identified as important to mount an integral response to oxidative stress, such as the Spt-Ada-Gcn5-acetyl transferase or Elongator complexes, respectively. With the aim of identifying new regulators of this massive gene expression program, we have used a GFP-based protein reporter and screened a fission yeast deletion collection using flow cytometry. We find that the levels of catalase fused to GFP, both before and after a threat of peroxides, are altered in hundreds of strains lacking components of chromatin modifiers, transcription complexes, and modulators of translation. Thus, the transcription elongation complex Paf1, the histone methylase Set1-COMPASS, and the translation-related Trm112 dimers are all involved in full expression of Ctt1-GFP and in wild-type tolerance to peroxides."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m115.696658"xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/author | "Garcia P."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/author | "Hidalgo E."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/author | "Ayte J."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/author | "Encinar Del Dedo J."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/pages | "790-799"xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/title | "Genome-wide Screening of Regulators of Catalase Expression: ROLE OF A TRANSCRIPTION COMPLEX AND HISTONE AND tRNA MODIFICATION COMPLEXES ON ADAPTATION TO STRESS."xsd:string |
| http://purl.uniprot.org/citations/26567340 | http://purl.uniprot.org/core/volume | "291"xsd:string |
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