| http://purl.uniprot.org/citations/26612263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26612263 | http://www.w3.org/2000/01/rdf-schema#comment | "Innate-like B-1a lymphocytes rapidly redistribute to regional mediastinal lymph nodes (MedLNs) during influenza infection to generate protective IgM. Here we demonstrate that influenza infection-induced type I interferons directly stimulate body cavity B-1 cells and are a necessary signal required for B-1 cell accumulation in MedLNs. Vascular mimetic flow chamber studies show that type I interferons increase ligand-mediated B-1 cell adhesion under shear stress by inducing high-affinity conformation shifts of surface-expressed integrins. In vivo trafficking experiments identify CD11b as the non-redundant, interferon-activated integrin required for B-1 cell accumulation in MedLNs. Thus, CD11b on B-1 cells senses infection-induced innate signals and facilitates their rapid sequester into secondary lymphoid tissues, thereby regulating the accumulation of polyreactive IgM producers at sites of infection."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms9991"xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Kalinke U."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Cherry S."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Baumgarth N."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Simon S.I."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Dixit N."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Hastey C.J."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Soo Choi Y."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/author | "Waffarn E.E."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/pages | "8991"xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/title | "Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation."xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/26612263 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26612263 |
| http://purl.uniprot.org/citations/26612263 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26612263 |
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| http://purl.uniprot.org/uniprot/#_A0A0X1KG58-mappedCitation-26612263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26612263 |
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| http://purl.uniprot.org/uniprot/#_A0A8Q0Q4S2-mappedCitation-26612263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26612263 |