| http://purl.uniprot.org/citations/26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26646451 | http://www.w3.org/2000/01/rdf-schema#comment | "miRNAs have been shown to play pivotal roles in the establishment and progression of colon cancer, but their underlying mechanisms are not fully understood. N-acetyltransferase NAA10 participates in many cellular processes, including tumorigenesis. Here we showed that miR-342-5p and miR-608 suppressed the tumorigenesis of colon cancer cells in vitro and in vivo by targeting NAA10 mRNA for degradation. Overexpression of miR-342-5p or miR-608 decreased NAA10 mRNA and protein levels and thereby suppressed cell proliferation, migration, and cell-cycle progression, as well as promoted apoptosis in SW480 and SW620 cells. More importantly, miR-342-5p and miR-608 significantly decreased the tumorigenic capacity of SW480 and SW620 cells in a mouse xenograft model. We also observed an inverse correlation between the expression of NAA10 and that of both miRNAs. Our results implicate miR-342-5p and miR-608 in colon cancer development and unveil the underlying mechanism of this phenomenon, which involves NAA10."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.org/dc/terms/identifier | "doi:10.18632/oncotarget.6458"xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Li B."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Jiang F."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Niu J."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Yang Q."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Jiang D."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Wei P."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Bai S."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/author | "Wan Z."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/name | "Oncotarget"xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/pages | "2709-2720"xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/title | "microRNA-342-5p and miR-608 inhibit colon cancer tumorigenesis by targeting NAA10."xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/26646451 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26646451 |
| http://purl.uniprot.org/citations/26646451 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26646451 |
| http://purl.uniprot.org/uniprot/#_B4DFG1-mappedCitation-26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26646451 |
| http://purl.uniprot.org/uniprot/#_B4DKJ7-mappedCitation-26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26646451 |
| http://purl.uniprot.org/uniprot/#_B7Z9N2-mappedCitation-26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26646451 |
| http://purl.uniprot.org/uniprot/#_P41227-mappedCitation-26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26646451 |
| http://purl.uniprot.org/uniprot/#_Q6P4J0-mappedCitation-26646451 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26646451 |