| http://purl.uniprot.org/citations/26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26659056 | http://www.w3.org/2000/01/rdf-schema#comment | "Release of promoter-proximal paused RNA polymerase II (Pol II) during early elongation is a critical step in transcriptional regulation in metazoan cells. Paused Pol II release is thought to require the kinase activity of cyclin-dependent kinase 9 (CDK9) for the phosphorylation of DRB sensitivity-inducing factor, negative elongation factor, and C-terminal domain (CTD) serine-2 of Pol II. We found that Pol II-associated factor 1 (PAF1) is a critical regulator of paused Pol II release, that positive transcription elongation factor b (P-TEFb) directly regulates the initial recruitment of PAF1 complex (PAF1C) to genes, and that the subsequent recruitment of CDK12 is dependent on PAF1C. These findings reveal cooperativity among P-TEFb, PAF1C, and CDK12 in pausing release and Pol II CTD phosphorylation."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.aad2338"xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Tang Z."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Yang W."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Yu M."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Ni T."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Roeder R.G."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/author | "Nakadai T."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/pages | "1383-1386"xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/title | "RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II."xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://purl.uniprot.org/core/volume | "350"xsd:string |
| http://purl.uniprot.org/citations/26659056 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26659056 |
| http://purl.uniprot.org/citations/26659056 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26659056 |
| http://purl.uniprot.org/uniprot/#_P13984-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_Q14241-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_B4DGJ5-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_P51946-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_P51948-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_P52434-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_P52435-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |
| http://purl.uniprot.org/uniprot/#_Q15369-mappedCitation-26659056 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26659056 |