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http://purl.uniprot.org/citations/26699787http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26699787http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26699787http://www.w3.org/2000/01/rdf-schema#comment"To identify substitutions that are possibly associated with the adaptation of avian-origin H10N7 virus to mammals, adaptation of the H10N7 virus in mouse lung was carried out by serial lung-to-lung passage. Genomic analysis of the mouse-adapted virus revealed amino acid changes in the PB2 (E627K), PA (T97I), and HA (G409E) proteins, and this virus was more virulent in mice than the wild-type virus. Our results suggest that these substitutions are involved in the enhancement of the replication efficiency of avian-origin H10N7 virus, resulting in severe disease in mice. Continued poultry surveillance of these substitutions in H10N7 viruses is required."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.org/dc/terms/identifier"doi:10.1007/s00705-015-2722-6"xsd:string
http://purl.uniprot.org/citations/26699787http://purl.org/dc/terms/identifier"doi:10.1007/s00705-015-2722-6"xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Cheng L."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Cheng L."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Lu X."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Lu X."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Peng X."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Peng X."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Yao H."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Yao H."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Wu H."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Wu H."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Wu N."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Wu N."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Xie T."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Xie T."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Jin C."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Jin C."xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Peng X.'"xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/author"Peng X.'"xsd:string
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/26699787http://purl.uniprot.org/core/date"2016"xsd:gYear