http://purl.uniprot.org/citations/26700685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26700685 | http://www.w3.org/2000/01/rdf-schema#comment | "A brain consists of numerous distinct neurons arising from a limited number of progenitors, called neuroblasts in Drosophila. Each neuroblast produces a specific neuronal lineage. To unravel the transcriptional networks that underlie the development of distinct neuroblast lineages, we marked and isolated lineage-specific neuroblasts for RNA sequencing. We labeled particular neuroblasts throughout neurogenesis by activating a conditional neuroblast driver in specific lineages using various intersection strategies. The targeted neuroblasts were efficiently recovered using a custom-built device for robotic single-cell picking. Transcriptome analysis of mushroom body, antennal lobe and type II neuroblasts compared with non-selective neuroblasts, neurons and glia revealed a rich repertoire of transcription factors expressed among neuroblasts in diverse patterns. Besides transcription factors that are likely to be pan-neuroblast, many transcription factors exist that are selectively enriched or repressed in certain neuroblasts. The unique combinations of transcription factors present in different neuroblasts may govern the diverse lineage-specific neuron fates."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.129163"xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Ren Q."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Yao X."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Liu L.Y."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Lee T."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Yang C.P."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Sugino K."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Lee L.P."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/author | "Fu C.C."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/name | "Development"xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/pages | "411-421"xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/title | "Transcriptomes of lineage-specific Drosophila neuroblasts profiled by genetic targeting and robotic sorting."xsd:string |
http://purl.uniprot.org/citations/26700685 | http://purl.uniprot.org/core/volume | "143"xsd:string |
http://purl.uniprot.org/citations/26700685 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26700685 |
http://purl.uniprot.org/citations/26700685 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26700685 |
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http://purl.uniprot.org/uniprot/#_A0A0B4KHI3-mappedCitation-26700685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26700685 |
http://purl.uniprot.org/uniprot/#_A0A0B4KEQ0-mappedCitation-26700685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26700685 |
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http://purl.uniprot.org/uniprot/#_A0A0B4LF18-mappedCitation-26700685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26700685 |
http://purl.uniprot.org/uniprot/#_A0A0B4LF27-mappedCitation-26700685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26700685 |