http://purl.uniprot.org/citations/26717478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26717478 | http://www.w3.org/2000/01/rdf-schema#comment | "Processes taking place in the secretory organelles require Ca2+ and Mn2+, which in yeast are supplied by the Pmr1 ion pump. Here we observed that in the yeast Hansenula polymorpha Ca2+ deficiency in the secretory pathway caused by Pmr1 inactivation is exacerbated by (i) the ret1-27 mutation affecting COPI-mediated vesicular transport, (ii) inactivation of the vacuolar Ca2+ ATPase Pmc1 and (iii) inactivation of Vps35, which is a component of the retromer complex responsible for protein transport between the vacuole and secretory organelles. The ret1-27 mutation also exerted phenotypes indicating alterations in transport between the vacuole and secretory organelles. These data indicate that ret1-27, pmc1 and vps35 affect a previously unknown Pmr1-independent route of the Ca2+ delivery to the secretory pathway. We also observed that the vacuolar protein carboxypeptidase Y receives additional modifications of its glycoside chains if it escapes the Vps10-dependent sorting to the vacuole."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0145915"xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/author | "Agaphonov M.O."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/author | "Ter-Avanesyan M.D."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/author | "Chechenova M.B."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/author | "Fokina A.V."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/author | "Karginov A.V."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/pages | "e0145915"xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/title | "Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca2+ in Hansenula polymorpha."xsd:string |
http://purl.uniprot.org/citations/26717478 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/26717478 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26717478 |
http://purl.uniprot.org/citations/26717478 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26717478 |
http://purl.uniprot.org/uniprot/#_P13586-mappedCitation-26717478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26717478 |
http://purl.uniprot.org/uniprot/#_P34110-mappedCitation-26717478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26717478 |
http://purl.uniprot.org/uniprot/#_P38929-mappedCitation-26717478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26717478 |
http://purl.uniprot.org/uniprot/P34110 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26717478 |
http://purl.uniprot.org/uniprot/P13586 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26717478 |
http://purl.uniprot.org/uniprot/P38929 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26717478 |