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http://purl.uniprot.org/citations/26743780http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26743780http://www.w3.org/2000/01/rdf-schema#comment"We aim to explore the associations of fascin-1 and cadherin-17 in gastric cancer (GC) to the clinicopathologic features and prognosis of GC. Case group included 204 GC tissues while control group comprised 204 paired adjacent cancer tissues. Expressions of fascin-1 and cadherin-17 were measured with immunohistochemistry and western blot and then analyzed statistically in relation to clinicopathologic features and survival time. Survival curve was drawn by Kaplan-Meier method, and independent prognostic factors were identified with Cox proportional hazards regression model. Fascin-1 was positively expressed in 45.1 % of GC tissues and in 27.5 % of adjacent cancer tissues, respectively (P < 0.05); cadherin-17 was positively expressed in 51.5 % of GC tissues and in 33.8 % of adjacent cancer tissues (P < 0.05). Fascin-1 expression in GC tissues was related to tumor size (P = 0.001) and Lauren classification (P = 0.001). Cadherin-17 expression in GC tissues was related to tumor size (P < 0.001), Lauren classification (P = 0.009), clinical staging (P = 0.001), and distant metastasis (P = 0.002). Fascin-1 expression was positively correlated with cadherin-17 expression in GC tissues (r = 0.828, P < 0.01). Patients with positive expression of both fascin-1 and cadherin-17 had lower survival rates than those with negative expression (all P < 0.01). Cox regression analysis showed that fascin-1 expression, cadherin-17 expression, tumor size, and differentiation were independent risk factors for GC (all P < 0.05). Fascin-1 and cadherin-17 are related to clinicopathologic features of GC and are independent adverse prognostic factors for GC."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.org/dc/terms/identifier"doi:10.1007/s13277-015-4368-0"xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Cao H."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Wang M."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Xu J."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Zuo J."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Zhang Y.Q."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Wang D.H."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Zhao W.Y."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Zhang Z.Z."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Tu L."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Zhu C.C."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/author"Tang D.F."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/name"Tumour Biol"xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/pages"8775-8782"xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/title"Correlations of fascin-1 and cadherin-17 protein expression with clinicopathologic features and prognosis of patients with gastric cancer."xsd:string
http://purl.uniprot.org/citations/26743780http://purl.uniprot.org/core/volume"37"xsd:string
http://purl.uniprot.org/citations/26743780http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26743780
http://purl.uniprot.org/citations/26743780http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26743780
http://purl.uniprot.org/uniprot/#_B4DVA8-mappedCitation-26743780http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26743780
http://purl.uniprot.org/uniprot/#_Q12864-mappedCitation-26743780http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26743780
http://purl.uniprot.org/uniprot/#_Q61553-mappedCitation-26743780http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26743780
http://purl.uniprot.org/uniprot/Q12864http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/26743780