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http://purl.uniprot.org/citations/26769430http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26769430http://www.w3.org/2000/01/rdf-schema#comment"

Context

Leptin is produced in white adipose tissue, but also in human coronary atherosclerotic lesions.

Objective

The aim of this study is to assess the prognostic value of leptin in patients with proven coronary artery disease (CAD) (N = 1907).

Methods

AtheroGene is a contemporary CAD cohort study (N = 3229). Median follow-up time was 3.8 (Quartile 1/3 with 2.8/4.9) years.

Results

Leptin concentration was associated with a hazard ratio (HR) for the fully adjusted model of HR = 1.32 in women but was not significant in men. The endpoint cardiovascular death and non-fatal myocardial infarction was observed in 167 patients.

Conclusion

In women with known CAD, increased leptin concentration is useful for predicting cardiovascular death and non-fatal myocardial infarction."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.org/dc/terms/identifier"doi:10.3109/1354750x.2015.1130745"xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Lackner K.J."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Blankenberg S."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Zeller T."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Bickel C."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Schnabel R.B."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Rupprecht H.J."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Westermann D."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/author"Sinning C."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/date"2017"xsd:gYear
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http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/pages"210-218"xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/title"Predictors of leptin concentration and association with cardiovascular risk in patients with coronary artery disease: results from the AtheroGene study."xsd:string
http://purl.uniprot.org/citations/26769430http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/26769430http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26769430
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