| http://purl.uniprot.org/citations/26769680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26769680 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated whether a single 60-min bout of whole leg, peristaltic pulse external pneumatic compression (EPC) altered select growth factor-related mRNAs and/or various phospho(p)-proteins related to cell growth, proliferation, inflammation and apoptosis signalling (e.g. Akt-mTOR, Jak-Stat). Ten participants (8 males, 2 females; aged 22·2 ± 0·4 years) reported to the laboratory 4 h post-prandial, and vastus lateralis muscle biopsies were obtained prior to (PRE), 1 h and 4 h post-EPC treatment. mRNA expression was analysed using real-time RT-PCR and phosphophorylated and cleaved proteins were analysed using an antibody array. No changes in selected growth factor-related mRNAs were observed following EPC. All p-proteins significantly altered by EPC decreased, except for p-rps6 (Ser235/236) which increased 31% 1 h post-EPC compared to PRE levels (P = 0·016). Notable decreases also included p-BAD (Ser112; -28%, P = 0·004) at 4 h post-EPC compared to PRE levels. In summary, an acute bout of EPC transiently upregulates p-rps6 as well as affecting other markers in the Akt-mTOR signalling cascade. Future research should characterize whether chronic EPC application promotes alterations in lower-limb musculature and/or enhances exercise-induced training adaptations."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.org/dc/terms/identifier | "doi:10.1111/cpf.12343"xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Roberts M.D."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Martin J.S."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Wilson T.J."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Goodlett M.D."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Kephart W.C."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/author | "Mobley C.B."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/name | "Clin Physiol Funct Imaging"xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/pages | "602-609"xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/title | "A single 60-min bout of peristaltic pulse external pneumatic compression transiently upregulates phosphorylated ribosomal protein s6."xsd:string |
| http://purl.uniprot.org/citations/26769680 | http://purl.uniprot.org/core/volume | "37"xsd:string |
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