http://purl.uniprot.org/citations/2681803 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/2681803 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/2681803 | http://www.w3.org/2000/01/rdf-schema#comment | "The C-SRC, C-YES, and FYN genes encode three closely related tyrosine protein kinases that are expressed in human neural tissues. A unique form of the C-SRC gene has been demonstrated to be expressed in avian and murine brain tissues as the result of alternative splicing between the third and fourth exons. This neuronal-specific splicing event adds to the C-SRC mRNA an 18 base pair exon capable of encoding the same six amino acids in both avian and murine neural tissues. The C-YES and FYN genes share with C-SRC similar exon-intron boundaries and a high degree of amino acid sequence homology in the 3/4 exon coding region. However, potential alternative splicing of the C-YES and FYN genes in this region has not been previously investigated. In this study we have compared the expression of C-SRC, C-YES, and FYN RNAs in human lung, liver, brain, and placenta tissues and prepared cDNA clones spanning exons 3 and 4 for each of these genes from the different tissues. Sequence analysis of these cDNA clones revealed that the splicing patterns for the FYN and C-YES genes were the same among the various tissues, whereas C-SRC cDNAs isolated from brain contained 18 additional bases with the capacity to code for the same six amino acids present in the neural-specific forms of avian and murine pp60c-src."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.org/dc/terms/identifier | "doi:10.1002/jnr.490240113"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.org/dc/terms/identifier | "doi:10.1002/jnr.490240113"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/author | "Bolen J.B."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/author | "Bolen J.B."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/author | "Pyper J.M."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/author | "Pyper J.M."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/name | "J. Neurosci. Res."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/name | "J. Neurosci. Res."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/pages | "89-96"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/pages | "89-96"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/title | "Neuron-specific splicing of C-SRC RNA in human brain."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/title | "Neuron-specific splicing of C-SRC RNA in human brain."xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/volume | "24"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://purl.uniprot.org/core/volume | "24"xsd:string |
http://purl.uniprot.org/citations/2681803 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2681803 |
http://purl.uniprot.org/citations/2681803 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2681803 |
http://purl.uniprot.org/citations/2681803 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2681803 |
http://purl.uniprot.org/citations/2681803 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2681803 |
http://purl.uniprot.org/uniprot/P12931 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2681803 |
http://purl.uniprot.org/uniprot/P12931#attribution-8B8304D26B683F4698322CBD71A23C3A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/2681803 |