http://purl.uniprot.org/citations/26825462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26825462 | http://www.w3.org/2000/01/rdf-schema#comment | "Meiosis-specific cohesin, required for the linking of the sister chromatids, plays a critical role in various chromosomal events during meiotic prophase I, such as chromosome morphogenesis and dynamics, as well as recombination. Rad61/Wpl1 (Wapl in other organisms) negatively regulates cohesin functions. In this study, we show that meiotic chromosome axes are shortened in the budding yeast rad61/wpl1 mutant, suggesting that Rad61/Wpl1 negatively regulates chromosome axis compaction. Rad61/Wpl1 is required for efficient resolution of telomere clustering during meiosis I, indicating a positive effect of Rad61/Wpl1 on the cohesin function required for telomere dynamics. Additionally, we demonstrate distinct activities of Rad61/Wpl1 during the meiotic recombination, including its effects on the efficient processing of intermediates. Thus, Rad61/Wpl1 both positively and negatively regulates various cohesin-mediated chromosomal processes during meiosis."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkw034"xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/author | "Lee M.S."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/author | "Kim K.P."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/author | "Shinohara M."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/author | "Shinohara A."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/author | "Challa K."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/name | "Nucleic Acids Res"xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/pages | "3190-3203"xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/title | "Rad61/Wpl1 (Wapl), a cohesin regulator, controls chromosome compaction during meiosis."xsd:string |
http://purl.uniprot.org/citations/26825462 | http://purl.uniprot.org/core/volume | "44"xsd:string |
http://purl.uniprot.org/citations/26825462 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26825462 |
http://purl.uniprot.org/citations/26825462 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26825462 |
http://purl.uniprot.org/uniprot/#_A0A8H8UMT4-mappedCitation-26825462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26825462 |
http://purl.uniprot.org/uniprot/#_Q12188-mappedCitation-26825462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26825462 |
http://purl.uniprot.org/uniprot/#_Q99359-mappedCitation-26825462 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26825462 |
http://purl.uniprot.org/uniprot/A0A8H8UMT4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26825462 |
http://purl.uniprot.org/uniprot/Q99359 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26825462 |
http://purl.uniprot.org/uniprot/Q12188 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26825462 |