| http://purl.uniprot.org/citations/26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26831757 | http://www.w3.org/2000/01/rdf-schema#comment | "Eukaryotic ribosomes assemble by association of ribosomal RNA with ribosomal proteins into nuclear precursor particles, which undergo a complex maturation pathway coordinated by non-ribosomal assembly factors. Here, we provide functional insights into how successive structural re-arrangements in ribosomal protein S3 promote maturation of the 40S ribosomal subunit. We show that S3 dimerizes and is imported into the nucleus with its N-domain in a rotated conformation and associated with the chaperone Yar1. Initial assembly of S3 with 40S precursors occurs via its C-domain, while the N-domain protrudes from the 40S surface. Yar1 is replaced by the assembly factor Ltv1, thereby fixing the S3 N-domain in the rotated orientation and preventing its 40S association. Finally, Ltv1 release, triggered by phosphorylation, and flipping of the S3 N-domain into its final position results in the stable integration of S3. Such a stepwise assembly may represent a new paradigm for the incorporation of ribosomal proteins."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms10336"xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Leulliot N."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Blaud M."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Delbos L."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Rety S."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Bergler H."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Pertschy B."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Kressler D."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Mitterer V."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Murat G."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/author | "Stanborough T."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/pages | "10336"xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/title | "Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation."xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/26831757 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26831757 |
| http://purl.uniprot.org/citations/26831757 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26831757 |
| http://purl.uniprot.org/uniprot/#_P34078-mappedCitation-26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26831757 |
| http://purl.uniprot.org/uniprot/#_P46683-mappedCitation-26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26831757 |
| http://purl.uniprot.org/uniprot/#_P05750-mappedCitation-26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26831757 |
| http://purl.uniprot.org/uniprot/#_P30822-mappedCitation-26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26831757 |
| http://purl.uniprot.org/uniprot/#_P38701-mappedCitation-26831757 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26831757 |