| http://purl.uniprot.org/citations/26843463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26843463 | http://www.w3.org/2000/01/rdf-schema#comment | "GABAergic interneurons play key roles in cortical circuits, yet little is known about their early connectivity. Here we use glutamate uncaging and a novel optogenetic strategy to track changes in the afferent and efferent synaptic connections of developing neocortical interneuron subtypes. We find that Nkx2-1-derived interneurons possess functional synaptic connections before emerging pyramidal cell networks. Subsequent interneuron circuit maturation is both subtype and layer dependent. Glutamatergic input onto fast spiking (FS), but not somatostatin-positive, non-FS interneurons increases over development. Interneurons of both subtype located in layers (L) 4 and 5b engage in transient circuits that disappear after the somatosensory critical period. These include a pathway mediated by L5b somatostatin-positive interneurons that specifically targets L4 during the first postnatal week. The innervation patterns of immature cortical interneuron circuits are thus neither static nor progressively strengthened but follow a layer-specific choreography of transient connections that differ from those of the adult brain."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms10584"xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Katzel D."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Marques-Smith A."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Miesenbock G."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Butt S.J."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Lickiss T."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Anastasiades P.G."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Lyngholm D."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/author | "Raffiq S."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/pages | "10584"xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/title | "GABAergic interneurons form transient layer-specific circuits in early postnatal neocortex."xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/26843463 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26843463 |
| http://purl.uniprot.org/citations/26843463 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26843463 |
| http://purl.uniprot.org/uniprot/#_P60041-mappedCitation-26843463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/#_Q3KP16-mappedCitation-26843463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/#_Q8K3P1-mappedCitation-26843463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/#_Q545V6-mappedCitation-26843463 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/P60041 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/Q545V6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26843463 |
| http://purl.uniprot.org/uniprot/Q8K3P1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26843463 |