| http://purl.uniprot.org/citations/26869068 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26869068 | http://www.w3.org/2000/01/rdf-schema#comment | "Hexanucleotide repeat expansions in C9orf72 are the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) (c9ALS/FTD). Unconventional translation of these repeats produces dipeptide repeat proteins (DPRs) that may cause neurodegeneration. We performed a modifier screen in Drosophila and discovered a critical role for importins and exportins, Ran-GTP cycle regulators, nuclear pore components, and arginine methylases in mediating DPR toxicity. These findings provide evidence for an important role for nucleocytoplasmic transport in the pathogenic mechanism of c9ALS/FTD."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep20877"xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Van Damme P."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Cruts M."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Van Broeckhoven C."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Steyaert J."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Van Den Bosch L."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Verstrepen K.J."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Gitler A.D."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Robberecht W."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Rousseau F."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Gijselinck I."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Callaerts P."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Schymkowitz J."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Bogaert E."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Sieben A."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Boeynaems S."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Scheveneels W."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "De Baets G."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Cuijt I."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Michiels E."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/author | "Jovicic A."xsd:string |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26869068 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |