| http://purl.uniprot.org/citations/26883254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26883254 | http://www.w3.org/2000/01/rdf-schema#comment | "The expression of sialic acid-binding Ig-like lectin (Siglec) family has been detected in many malignant tumors and correlated with patient outcomes. The present study aims to investigate the prognostic value of Siglec-8 expression and refine current risk stratification system in patients with gastric cancer. Two independent sets of patients (n = 78; n = 356, respectively) with gastric cancer from Zhongshan Hospital were enrolled into this study. The expression of Siglec-8 was detected by immunohistochemistry. Cox regression analysis was used to assess the prognostic value of Siglec-8 expression and clinical outcomes. A novel molecular prognostic stratification system combining intratumoral Siglec-8 expression with TNM stage was determined by means of receiver operating characteristic analysis. Multivariate Cox regression analysis identified that intratumoral Siglec-8 low expression was an independent prognostic factor for dismal overall survival of patients with gastric cancer. Incorporating intratumoral Siglec-8 expression into the current TNM staging system showed more accuracy for predicting prognosis of patients with gastric cancer. Our study suggested that intratumoral Siglec-8 expression was an independent prognostic factor for overall survival of patients with gastric cancer. Incorporating Siglec-8 expression level into current TNM staging system might add more comprehensive prognostic information for patients with gastric cancer and lead to a more precise risk stratification system for predicting clinical outcomes."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.org/dc/terms/identifier | "doi:10.1007/s13277-016-4859-7"xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Cao Y."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Liu H."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Li R."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Lin C."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Zhang W."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Xu J."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/author | "Shen Z."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/name | "Tumour Biol"xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/pages | "10883-10891"xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/title | "Decreased expression of Siglec-8 associates with poor prognosis in patients with gastric cancer after surgical resection."xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/26883254 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26883254 |
| http://purl.uniprot.org/citations/26883254 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26883254 |
| http://purl.uniprot.org/uniprot/#_C9JT30-mappedCitation-26883254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26883254 |
| http://purl.uniprot.org/uniprot/#_Q9NYZ4-mappedCitation-26883254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26883254 |
| http://purl.uniprot.org/uniprot/Q9NYZ4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26883254 |
| http://purl.uniprot.org/uniprot/C9JT30 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26883254 |