http://purl.uniprot.org/citations/26910737 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26910737 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo examine potential correlations between maternal serum placental protein-13 (PP-13) and first trimester maternal and placental factors, and to evaluate the association of this marker with adverse pregnancy outcome.MethodsSerum samples from prospectively enrolled patients between 11 and 13 weeks and 6 days were analyzed for PP-13 using an ELISA assay. The relationships between maternal serum PP-13 levels and gestational age, maternal age, ethnicity, parity, smoking status, body mass index (BMI), mean arterial blood pressure, uterine and umbilical artery Doppler parameters were examined. The association between first-trimester PP-13 levels and subsequent pre-eclampsia and delivery of a small for gestational age (SGA) neonate was also investigated, after excluding patients who received aspirin.ResultsIn 908 patients, PP-13 levels ranged from 8.0 to 537.5 pg/mL. A significant negative correlation was identified between PP13 and BMI (Spearman rho -0.20, P<0.0001). Smoking significantly decreased PP-13 (P<0.01). No relationship was identified with the other parameters. In a subgroup of 668 low-risk patients who did not receive aspirin, PP-13 levels were not associated with development of pre-eclampsia, SGA or the combination of them.ConclusionFirst-trimester PP-13 levels are significantly correlated with BMI and smoking. These correlations appear independent of uterine and umbilical artery resistance. In low risk patients, PP-13 levels fail to predict the risk for pre-eclampsia or SGA."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.org/dc/terms/identifier | "doi:10.1515/jpm-2015-0324"xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/author | "Meiri H."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/author | "Blitzer M."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/author | "Grimpel Y.I."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/author | "Baschat A.A."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/author | "Seravalli V."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/name | "J Perinat Med"xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/pages | "543-549"xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/title | "Relationship between first-trimester serum placental protein-13 and maternal characteristics, placental Doppler studies and pregnancy outcome."xsd:string |
http://purl.uniprot.org/citations/26910737 | http://purl.uniprot.org/core/volume | "44"xsd:string |
http://purl.uniprot.org/citations/26910737 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26910737 |
http://purl.uniprot.org/citations/26910737 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26910737 |
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http://purl.uniprot.org/uniprot/Q1M314 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26910737 |
http://purl.uniprot.org/uniprot/Q9UHV8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/26910737 |