http://purl.uniprot.org/citations/26932430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26932430 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundTo evaluate the expression of beta-catenin (β-catenin) and SKP2 proteins in superficial bladder cancer cases and their correlation with tumor grade and stage.MethodsAfter institutional review board approval, we retrospectively evaluated the expression of β-catenin and SKP2 proteins in tissue specimens from patients with non-muscle invasive bladder cancer (NMIBC) and compared their results with a cohort of chronic nonspecific cystitis's. Then we and explored these markers association with tumor grade and stage.ResultsA total of 40 patients were retrospectively identified, 50% was NMIBC and the rest were chronic nonspecific cystitis. β-catenin was expressed in 18 (90%) patients of the NMIBC group in comparison to 14 (70%) of the control group with (P=0.1), while SKP2 protein was only expressed in NMIBC groups (P=0.03). A statistically significant correlation was identified between nucleocytoplasmic localization of β-catenin and SKP2 with tumor grade, stage.Conclusionsβ-catenin and SKP2 expression are providing promising results for differentiating higher grade and stage non muscle invasive bladder cancers."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.org/dc/terms/identifier | "doi:10.3978/j.issn.2304-3865.2016.02.02"xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Dawood M."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Gaber M.A."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Elkady N."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Badawy A."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Elbaky T.A."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Elserafy F."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Elsherif E."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/author | "Gharabawy M.E."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/name | "Chin Clin Oncol"xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/pages | "6"xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/title | "beta-catenin and SKP2 proteins as predictors of grade and stage of non-muscle invasive urothelial bladder carcinoma."xsd:string |
http://purl.uniprot.org/citations/26932430 | http://purl.uniprot.org/core/volume | "5"xsd:string |
http://purl.uniprot.org/citations/26932430 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26932430 |
http://purl.uniprot.org/citations/26932430 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26932430 |
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http://purl.uniprot.org/uniprot/#_B4DHK6-mappedCitation-26932430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26932430 |
http://purl.uniprot.org/uniprot/#_D6R9R7-mappedCitation-26932430 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26932430 |