| http://purl.uniprot.org/citations/26974660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26974660 | http://www.w3.org/2000/01/rdf-schema#comment | "The Ndc80 complex (Ndc80, Nuf2, Spc24 and Spc25) is a highly conserved kinetochore protein essential for end-on anchorage to spindle microtubule plus ends and for force generation coupled to plus-end polymerization and depolymerization. Spc24/Spc25 at one end of the Ndc80 complex binds the kinetochore. The N-terminal tail and CH domains of Ndc80 bind microtubules, and an internal domain binds microtubule-associated proteins (MAPs) such as the Dam1 complex. To determine how the microtubule- and MAP-binding domains of Ndc80 contribute to force production at the kinetochore in budding yeast, we have inserted a FRET tension sensor into the Ndc80 protein about halfway between its microtubule-binding and internal loop domains. The data support a mechanical model of force generation at metaphase where the position of the kinetochore relative to the microtubule plus end reflects the relative strengths of microtubule depolymerization, centromere stretch and microtubule-binding interactions with the Ndc80 and Dam1 complexes."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb3323"xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Erickson H.P."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Ohashi T."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Salmon E.D."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Bloom K."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Haase J."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/author | "Badger B.L."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/name | "Nat Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/pages | "382-392"xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/title | "How the kinetochore couples microtubule force and centromere stretch to move chromosomes."xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/26974660 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26974660 |
| http://purl.uniprot.org/citations/26974660 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26974660 |
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| http://purl.uniprot.org/uniprot/#_P33895-mappedCitation-26974660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26974660 |
| http://purl.uniprot.org/uniprot/#_Q12248-mappedCitation-26974660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26974660 |
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| http://purl.uniprot.org/uniprot/#_P69850-mappedCitation-26974660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26974660 |
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