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http://purl.uniprot.org/citations/26980223http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26980223http://www.w3.org/2000/01/rdf-schema#comment"Mutations of the epigenetic enzymes isocitrate dehydrogenase (IDH) 1 and 2, and the methylcytosine dioxygenase 'ten-eleven translocation 2' (TET2), are common in human myeloid malignancies and drivers of these disorders but the underlying mechanisms remain obscure. This review examines mutant IDH1/2 and TET2 enzymes in the context of responses to DNA damage and their potential involvement in age-related genomic instability. The clinical relevance of these findings and their potential application in novel therapeutic strategies is also discussed."xsd:string
http://purl.uniprot.org/citations/26980223http://purl.org/dc/terms/identifier"doi:10.1007/s12185-016-1973-7"xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/author"Inoue S."xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/author"Mak T.W."xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/author"Lemonnier F."xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/name"Int J Hematol"xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/pages"627-633"xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/title"Roles of IDH1/2 and TET2 mutations in myeloid disorders."xsd:string
http://purl.uniprot.org/citations/26980223http://purl.uniprot.org/core/volume"103"xsd:string
http://purl.uniprot.org/citations/26980223http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26980223
http://purl.uniprot.org/citations/26980223http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26980223
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http://purl.uniprot.org/uniprot/#_O75874-mappedCitation-26980223http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26980223
http://purl.uniprot.org/uniprot/#_P48735-mappedCitation-26980223http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/26980223
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