| http://purl.uniprot.org/citations/27100389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27100389 | http://www.w3.org/2000/01/rdf-schema#comment | "The Vcx1-M1 mutant is known to confer calcineurin-dependent Mn(2+) tolerance in budding yeast. Here, we demonstrate that another Vcx1 mutant, Vcx1-D1 with calcineurin-independent vacuolar Ca(2+)/H(+) exchanger activity, confers calcineurin-independent Mn(2+) tolerance. Unlike Vcx1-M1, the Mn(2+) tolerance conferred by Vcx1-D1 is dependent on the presence of Pmr1 or Pmc1. The Pmr1-dependent Mn(2+) tolerance of Vcx1-D1 requires the presence of calcineurin but not the functioning of the Ca(2+)/calcineurin signaling pathway. Similar to the wild-type Vcx1, C-terminally green fluorescent protein tagged Vcx1-D1 and Vcx1-M1 mutants localize to the endoplasmic reticulum instead of its normal vacuolar destination, but they remain functional in Ca(2+) sensitivity and Mn(2+) tolerance."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.org/dc/terms/identifier | "doi:10.1139/cjm-2015-0595"xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/author | "Jiang L."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/author | "Xu H."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/author | "Zhao Y."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/name | "Can J Microbiol"xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/pages | "475-484"xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/title | "Vcx1-D1 (M383I), the Vcx1 mutant with a calcineurin-independent vacuolar Ca(2+)/H(+) exchanger activity, confers calcineurin-independent Mn(2+) tolerance in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://purl.uniprot.org/core/volume | "62"xsd:string |
| http://purl.uniprot.org/citations/27100389 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27100389 |
| http://purl.uniprot.org/citations/27100389 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27100389 |
| http://purl.uniprot.org/uniprot/#_P13586-mappedCitation-27100389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27100389 |
| http://purl.uniprot.org/uniprot/#_P38929-mappedCitation-27100389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27100389 |
| http://purl.uniprot.org/uniprot/#_Q99385-mappedCitation-27100389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27100389 |
| http://purl.uniprot.org/uniprot/Q99385 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27100389 |
| http://purl.uniprot.org/uniprot/P13586 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27100389 |
| http://purl.uniprot.org/uniprot/P38929 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27100389 |