| http://purl.uniprot.org/citations/27193470 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27193470 | http://www.w3.org/2000/01/rdf-schema#comment | "The Fc receptor-like (FCRL) molecules have recently been shown to contribute to the pathogenesis of certain autoimmune disorders. In this study, we investigated the expression levels of FCRL1, 2 and 4 in blood mononuclear cells from rheumatoid arthritis patients using real-time PCR. The mRNA of these molecules was detected in 44.4 % (FCRL1), 53.3 % (FCRL2) and 31.1 % (FCRL4) of patients. Comparatively, 31.1 % (FCRL1), 51.1 % (FCRL2) and 26.6 % (FCRL4) of controls expressed these genes. Analysis of gene expressions in FCRL-positive patients demonstrated a lower FCRL4 gene expression in patients compared to controls (P < 0.001). In FCRL2-positive patients, a significant positive correlation between FCRL2 expression and the erythrocyte sedimentation rate (P < 0.001), anti-cyclic citrullinated peptide antibody (P = 0.033) level and disease activity score (DAS28, P = 0.016) was found. In conclusion, decreased FCRL4 expression and association of FCRL2 expression with inflammatory markers and disease activity suggested the contribution of these molecules to RA inflammatory processes."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00296-016-3495-2"xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/author | "Hosseini A."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/author | "Amirghofran Z."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/author | "Habibagahi Z."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/author | "Khanzadeh A."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/name | "Rheumatol Int"xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/pages | "1149-1156"xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/title | "Investigation of the human FCRL1, 2, and 4 gene expressions in patients with rheumatoid arthritis."xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/27193470 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27193470 |
| http://purl.uniprot.org/citations/27193470 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27193470 |
| http://purl.uniprot.org/uniprot/#_Q96PJ5-mappedCitation-27193470 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27193470 |
| http://purl.uniprot.org/uniprot/Q96PJ5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27193470 |