| http://purl.uniprot.org/citations/2721933 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2721933 | http://www.w3.org/2000/01/rdf-schema#comment | "Recently a candidate gene for the primary testis-determining factor (TDF) encoding a zinc finger protein (ZFY) has been cloned from the human Y chromosome. A highly homologous X-linked copy has also been identified. Using this human sequence it is possible to identify two Y loci, an X and an autosomal locus in the mouse (Zfy-1, Zfy-2, Zfx and Zfa, respectively). Suprisingly ZFY is more homologous to the mouse X and autosomal sequences than it is to either of the Y-linked loci. Both Zfy-1 and Zfy-2 are present in the Sxr region of the Y but Zfy-2 is absent in the Sxr deletion variant Sxrb (or Sxr") suggesting it is not necessary for male determination. Extensive backcross analyses map Zfa to mouse chromosome 10 and Zfx to a 5-cM interval between anonymous X probe MDXS120 and the tabby locus (Ta). We also show that the mouse androgen receptor locus (m-AR) believed to underlie the testicular feminization mutation (Tfm) shows complete linkage to Zfx. Comparative mapping indicates that in man these genes lie in separate conserved DNA segments."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/121.4.803"xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Simon D."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Ferguson-Smith M."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Bishop C."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Mitchell M."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Affara N."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/author | "Avner P."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/pages | "803-809"xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/title | "Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region."xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://purl.uniprot.org/core/volume | "121"xsd:string |
| http://purl.uniprot.org/citations/2721933 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2721933 |
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