| http://purl.uniprot.org/citations/27230807 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27230807 | http://www.w3.org/2000/01/rdf-schema#comment | "Podocytes are dynamic polarized cells that lie on the surface of glomerular capillaries and comprise an essential component of the glomerular filtration barrier. Insulin provoked a sustained, approximately 70%, increase in intracellular calcium concentration in podocytes. RT-PCR revealed the presence of mRNA encoding sarco/endoplasmic reticulum calcium ATPase isoforms 1-3, and plasma membrane Ca(2+) pump (PMCA) isoforms 1,3,4; mRNA levels were depressed by the addition of insulin. Inhibitors of PMCA, and the Na(+) -Ca(2+) exchanger, increased podocyte permeability to albumin, induced dimerization of protein kinase G type I alpha (PKGIα), and activation of PKGIα-dependent signaling. These data suggest the involvement of calcium and PKGIα signaling in insulin-enhanced filtration barrier permeability in podocytes."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.org/dc/terms/identifier | "doi:10.1002/1873-3468.12228"xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Jankowski M."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Angielski S."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Piwkowska A."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Rogacka D."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Audzeyenka I."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/author | "Kasztan M."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/pages | "1739-1748"xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/title | "Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIalpha-dependent pathway."xsd:string |
| http://purl.uniprot.org/citations/27230807 | http://purl.uniprot.org/core/volume | "590"xsd:string |
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