http://purl.uniprot.org/citations/27238968 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27238968 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27238968 | http://www.w3.org/2000/01/rdf-schema#comment | "Chitin is the major component of fungal cell wall and serves as a molecular pattern that can be recognized by the receptor OsCEBiP in rice, a lysine motif (LysM) receptor-like protein (RLP), to trigger immune responses. The molecular mechanisms underlying chitin recognition remain elusive. Here we report the crystal structures of the ectodomain of OsCEBiP (OsCEBiP-ECD) in free and chitin-bound forms. The structures reveal that OsCEBiP-ECD contains three tandem LysMs followed by a novel structure fold of cysteine-rich domain. The structures showed that chitin binding induces no striking conformational changes in OsCEBiP. Structural comparison among N-acetylglucosamine (NAG) oligomer-bound LysMs revealed a highly conserved recognition mechanism, which is expected to facilitate study of other LysM-containing proteins for their NAG binding. Modeling study showed that chitin induces OsCEBiP homodimerization in a "sliding mode". Our data provide insights into rice chitin receptor-mediated immunity triggered by fungal cell wall."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2016.04.014"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2016.04.014"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Liu S."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Liu S."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Gong X."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Gong X."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Han Z."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Han Z."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Chai J."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/author | "Chai J."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/pages | "1192-1200"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/pages | "1192-1200"xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/title | "Molecular mechanism for fungal cell wall recognition by rice chitin receptor OsCEBiP."xsd:string |
http://purl.uniprot.org/citations/27238968 | http://purl.uniprot.org/core/title | "Molecular mechanism for fungal cell wall recognition by rice chitin receptor OsCEBiP."xsd:string |