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http://purl.uniprot.org/citations/27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27253156http://www.w3.org/2000/01/rdf-schema#comment"An animal embryo cannot initiate its journey of forming a new life on its own. It must rely on maternally provided resources and inputs to kick-start its developmental process. In Drosophila, the initial polarities of the embryo along both the anterior-posterior (AP) and dorsal-ventral (DV) axes are also specified by maternal determinants. Over the past several decades, genetic and molecular studies have identified and characterized such determinants, as well as the zygotic genetic regulatory networks that control patterning in the early embryo. Extensive studies of oogenesis have also led to a detailed knowledge of the cellular and molecular interactions that control the formation of a mature egg. Despite these efforts, oogenesis and embryogenesis have been studied largely as separate problems, except for qualitative aspects with regard to maternal regulation of the asymmetric localization of maternal determinants. Can oogenesis and embryogenesis be viewed from a unified perspective at a quantitative level, and can that improve our understanding of how robust embryonic patterning is achieved? Here, we discuss the basic knowledge of the regulatory mechanisms controlling oogenesis and embryonic patterning along the AP axis. We explore properties of the maternal Bicoid gradient in relation to embryo size in search for a unified framework for robust AP patterning. WIREs Dev Biol 2016, 5:562-581. doi: 10.1002/wdev.235 For further resources related to this article, please visit the WIREs website."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.org/dc/terms/identifier"doi:10.1002/wdev.235"xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/author"He F."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/author"Ma J."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/author"Xie G."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/author"Deng W.M."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/name"Wiley Interdiscip Rev Dev Biol"xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/pages"562-581"xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/title"Maternal AP determinants in the Drosophila oocyte and embryo."xsd:string
http://purl.uniprot.org/citations/27253156http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/27253156http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27253156
http://purl.uniprot.org/citations/27253156http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27253156
http://purl.uniprot.org/uniprot/#_A0A0B4KGY5-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_B5RIE4-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P09081-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P09085-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P25158-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P18102-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P05084-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P08044-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P25724-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_P39572-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156
http://purl.uniprot.org/uniprot/#_M9PDI3-mappedCitation-27253156http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27253156