Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27270225http://www.w3.org/2000/01/rdf-schema#comment"

Objective

The aim of the present study was to determine gingival crevicular fluid (GCF) levels of monocyte chemotactic protein-1 (MCP-1), regulated on activation, normal T-cell expressed and secreted protein (RANTES) and macrophage migration inhibitory factor (MIF) in metabolic syndrome patients with gingivitis.

Design

Twenty metabolic syndrome patients with gingivitis (MSG), 20 MetS patients with clinically healthy periodontium (MSH), 20 systemically healthy subjects with gingivitis and 20 subjects who were both systemically and periodontally healthy were included. Periodontal and systemical parameters were recorded. GCF MCP-1, RANTES and MIF levels were assayed by enzyme-linked immunosorbent assay method.

Results

MSG and MSH groups had elevated blood pressure, triglyceride, waist circumference and fasting glucose values in comparison to gingivitis and healthy groups (P<0.0001). Clinical periodontal parameters were higher in MSG and gingivitis groups when compared to those of the MSH and healthy groups (P<0.0001). MCP-1 and RANTES levels (ng/mg total protein) of MSG group were higher than those of the MSH groups (P=0.005, P=0.0001, respectively). Also gingivitis group had higher MCP-1, RANTES and MIF levels compared to the healthy group (P=0.011, P=0.0001, P=0.011 respectively). The RANTES level of MSG group was significantly higher than those of the gingivitis group (P=0.01), but MCP-1 and MIF levels were similar in the MSG and gingivitis groups (P>0.05).

Conclusion

Elevated levels of GCF RANTES in MetS patients with gingivitis might associate with the presence of increased gingival inflammation by MetS. Low-grade systemic inflammation associated with MetS and adipose tissue-derived RANTES might lead to altered GCF RANTES levels in the presence of gingival inflammation."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.org/dc/terms/identifier"doi:10.1016/j.archoralbio.2016.05.011"xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Atilla G."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Gurkan A."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Akcay Y.D."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Emingil G."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Cetinkalp S."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/author"Eren G."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/name"Arch Oral Biol"xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/pages"82-88"xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/title"Monocyte chemotactic protein-1, RANTES and macrophage migration inhibitory factor levels in gingival crevicular fluid of metabolic syndrome patients with gingivitis."xsd:string
http://purl.uniprot.org/citations/27270225http://purl.uniprot.org/core/volume"69"xsd:string
http://purl.uniprot.org/citations/27270225http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27270225
http://purl.uniprot.org/citations/27270225http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27270225
http://purl.uniprot.org/uniprot/#_D0EI67-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_P14174-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_A0A494C1Q1-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_B2R5J8-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_I4AY87-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_J3KRT7-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_P13500-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_P13501-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
http://purl.uniprot.org/uniprot/#_Q6UZ82-mappedCitation-27270225http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27270225
▶