| http://purl.uniprot.org/citations/27276346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27276346 | http://www.w3.org/2000/01/rdf-schema#comment | "Data on interleukin-31 (IL-31) involvement in the patho-genesis of mastocytosis, and its impact on pruritus development in the disease, are limited. The aim of this study was to analyse distinct IL-31 gene polymorphisms in 127 patients (age 0.5-76 years) with mastocytosis and their correlation with clinical presentation, pruritus and serum IL-31 levels. In patients with mastocytosis, the frequency of IL-31 IVS2+12AA genotype and IVS2+12A allele was higher than in control subjects and they were linked to an increased risk of development of mastocytosis. In adult patients, but not in children, -2057AA genotype was also associated with an increased risk of occurrence of mastocytosis. Pruritus affected 83.3% of 78 adult patients with mastocytosis, and a positive correlation between serum IL-31 levels and pruritus was found in these patients. In conclusion, distinct polymorphic variants of the IL-31 gene may be involved in the patho-genesis of mastocytosis, and IL-31 may be involved in the induction of pruritus in patients with mastocytosis."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.org/dc/terms/identifier | "doi:10.2340/00015555-2474"xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Lange M."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Sikorska M."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Gorska A."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Nowicki R."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Niedoszytko M."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Nedoszytko B."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Zawadzka A."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Rebala K."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Sokolowska-Wojdylo M."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Glen J."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Zablotna M."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/author | "Lugowska-Umer H."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/name | "Acta Derm Venereol"xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/pages | "47-53"xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/title | "Interleukin-31 Polymorphisms and Serum IL-31 Level in Patients with Mastocytosis: Correlation with Clinical Presen-tation and Pruritus."xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://purl.uniprot.org/core/volume | "97"xsd:string |
| http://purl.uniprot.org/citations/27276346 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27276346 |
| http://purl.uniprot.org/citations/27276346 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27276346 |
| http://purl.uniprot.org/uniprot/#_Q6EBC2-mappedCitation-27276346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27276346 |
| http://purl.uniprot.org/uniprot/Q6EBC2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27276346 |