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http://purl.uniprot.org/citations/27278897http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27278897http://www.w3.org/2000/01/rdf-schema#comment"Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is one of the major pre-mRNA-binding proteins, that is involved in translational modifications. In our previous studies, we found that hnRNP K is associated with human gastric cancer. The protein levels of hnRNP K were detected in cell lines and tissue microarrays. The correlation between hnRNP K expression and patient survival rate was evaluated by Kaplan-Meier survival analysis. In addition, we also detected hnRNP K expression in preoperative and postoperative serum samples from patients with gastric cancer, and serum samples from healthy volunteers. We found that hnRNP K was overexpressed in the gastric cancer cell lines. The levels of hnRNP K were significantly elevated in the gastric cancer tissues compared with that noted in the tumor-adjacent gastric mucosal and normal gastric mucosal sampes, and hnRNP K expression was found to correlate with tumor stage and lymph node metastasis. However, the level of serum hnRNP K did not differ significantly between gastric cancer patients and healthy volunteers. We also found that patients whose tumors showed elevated expression of hnRNP K had poor survival. The present study suggests that hnRNP K is a promising tissue biomarker for diagnosing gastric cancer and is a prognostic indicator for patients with gastric cancer."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.org/dc/terms/identifier"doi:10.3892/or.2016.4845"xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Chen Z."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Fu Y."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Yang R."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Xu H."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Wang P."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Zeng X."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Zhong J."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Zeng Y."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Yin Y."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Zeng M."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"You Q."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/author"Xiang M."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/name"Oncol Rep"xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/pages"929-935"xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/title"Heterogeneous nuclear ribonucleoprotein K is overexpressed and associated with poor prognosis in gastric cancer."xsd:string
http://purl.uniprot.org/citations/27278897http://purl.uniprot.org/core/volume"36"xsd:string
http://purl.uniprot.org/citations/27278897http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27278897
http://purl.uniprot.org/citations/27278897http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27278897
http://purl.uniprot.org/uniprot/#_B4DFF1-mappedCitation-27278897http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27278897
http://purl.uniprot.org/uniprot/#_B3KU16-mappedCitation-27278897http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27278897
http://purl.uniprot.org/uniprot/#_B4DUQ1-mappedCitation-27278897http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27278897