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http://purl.uniprot.org/citations/27380996http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27380996http://www.w3.org/2000/01/rdf-schema#comment"CREB binding protein (CBP) and p300 are critical regulators of hematopoiesis through both their transcriptional coactivator and acetyltransferase activities. Loss or mutation of CBP/p300 results in hematologic deficiencies in proliferation and differentiation as well as disruption of hematopoietic stem cell renewal and the microenvironment. Aberrant lysine acetylation mediated by CBP/p300 has recently been implicated in the genesis of multiple hematologic cancers. Understanding the effects of disrupting the acetyltransferase activity of CBP/p300 could pave the way for new therapeutic approaches to treat patients with these diseases."xsd:string
http://purl.uniprot.org/citations/27380996http://purl.org/dc/terms/identifier"doi:10.1016/j.ymgme.2016.06.013"xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/author"Dutta R."xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/author"Sakamoto K.M."xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/author"Tiu B."xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/name"Mol Genet Metab"xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/pages"37-43"xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/title"CBP/p300 acetyltransferase activity in hematologic malignancies."xsd:string
http://purl.uniprot.org/citations/27380996http://purl.uniprot.org/core/volume"119"xsd:string
http://purl.uniprot.org/citations/27380996http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27380996
http://purl.uniprot.org/citations/27380996http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27380996
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