http://purl.uniprot.org/citations/27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27414851 | http://www.w3.org/2000/01/rdf-schema#comment | "The store-operated Ca2+ entry-associated regulatory factor (SARAF), a protein expressed both in the endoplasmic reticulum and the plasma membrane, has been presented as a STIM1-interacting protein with the ability to modulate intracellular Ca2+ homeostasis. SARAF negatively modulates store-operated Ca2+ entry (SOCE) by preventing STIM1 spontaneous activation and regulating STIM1-Orai1 complex formation. In addition, SARAF is a negative regulator of Ca2+ entry through the arachidonate-regulated Ca2+ (ARC) channels. Here we explored the possible role of the surface expression of SARAF on the location of STIM1 in the plasma membrane. In NG115-401L cells, lacking a detectable expression of native STIM1, transfection with pHluorin-STIM1, which is able to translocate to the cell surface, enhances the plasma membrane location of SARAF as compared to cells transfected with YFP-STIM1, lacking the ability to translocate to the cell surface. These findings suggest that the surface location of SARAF is dependent on the expression of STIM1 in the plasma membrane."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.org/dc/terms/identifier | "doi:10.1080/19336950.2016.1212141"xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/author | "Albarran L."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/author | "Lopez J.J."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/author | "Rosado J.A."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/author | "Salido G.M."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/author | "Regodon S."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/name | "Channels (Austin)"xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/pages | "84-88"xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/title | "Role of STIM1 in the surface expression of SARAF."xsd:string |
http://purl.uniprot.org/citations/27414851 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/27414851 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27414851 |
http://purl.uniprot.org/citations/27414851 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27414851 |
http://purl.uniprot.org/uniprot/#_G0XQ39-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_B3KSV1-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_A0A140VK59-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_B7Z307-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_Q13586-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_Q96BY9-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/#_V5J3L2-mappedCitation-27414851 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/Q13586 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/G0XQ39 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27414851 |
http://purl.uniprot.org/uniprot/V5J3L2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27414851 |