| http://purl.uniprot.org/citations/2746374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2746374 | http://www.w3.org/2000/01/rdf-schema#comment | "Newcastle disease virus (NDV) infection in chickens differing in vitamin A status has been selected as a model to examine the interrelationship between marginal vitamin A deficiency and the severity of consequences of measles infection in humans. Day-old chickens with limited vitamin A reserves, the progeny of marginally vitamin A-deficient hens, were fed purified diets containing either marginal (120 retinol equivalents/kg diet, ad libitum) or adequate (1200 retinol equivalents/kg diet, ad libitum or pair-fed) levels of vitamin A for a period of 10 wk. At 4 wk of age, half of the chickens in each group were infected intraocularly with the lentogenic, i.e., mildly pathogenic, La Sota strain of NDV. Within 1 wk of infection, plasma retinol levels in the infected, marginally vitamin A-deficient chickens showed a significant and persistent decrease compared to their noninfected counterparts fed the same diet. Moreover, infection with NDV resulted in increased rates of morbidity in the marginally vitamin A-deficient chickens compared with nondeficient chickens. The results of this study indicate that pre-existing marginal vitamin A status increases the severity of disease following NDV infection, and that infection with NDV reduces marginal plasma vitamin A levels to levels which can be regarded as deficient."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.org/dc/terms/identifier | "doi:10.1093/jn/119.6.932"xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/author | "West C.E."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/author | "Rombout J.H."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/author | "Sijtsma S.R."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/author | "Van der Zijpp A.J."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/name | "J Nutr"xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/pages | "932-939"xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/title | "The interaction between vitamin A status and Newcastle disease virus infection in chickens."xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://purl.uniprot.org/core/volume | "119"xsd:string |
| http://purl.uniprot.org/citations/2746374 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2746374 |
| http://purl.uniprot.org/citations/2746374 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2746374 |
| http://purl.uniprot.org/uniprot/P19121#attribution-CC42709E961DB7155C933F52065AE9F4 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/2746374 |