| http://purl.uniprot.org/citations/27513891 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27513891 | http://www.w3.org/2000/01/rdf-schema#comment | "Follicular lymphoma (FL) shows co-expression of B-cell lymphoma 2 (BCL2) and CD10, whereas downexpression of CD10 is occasionally experienced in gastrointestinal (GI) FL with unknown significance. Gastrointestinal FL is a rare variant of FL, and its similarity with mucosa-associated lymphoid tissue lymphoma was reported. We investigated the clinicopathological and genetic features of CD10 downexpressed (CD10down ) GI-FL. The diagnosis of CD10down FL was carried out with a combination of pathological and molecular analyses. The incidence of CD10down GI-FL was shown in 35/172 (20.3%) cases, which was more frequent than nodal FL (3.5%, P < 0.001). The difference was additionally significant between GI-FL and nodal FL when the analysis was confined to primary GI-FL (55.2% vs 3.5%, P < 0.001). Compared to CD10+ GI-FL, CD10down GI-FL significantly involved the stomach or large intestine (P = 0.015), and additionally showed the downexpression of BCL6 (P < 0.001). The follicular dendritic cell meshwork often showed a duodenal pattern in the CD10down group (P = 0.12). Furthermore, a lymphoepithelial lesion was observed in 5/12 (40%) gastric FL cases, which indicated caution in the differentiation of mucosa-associated lymphoid tissue lymphoma. Molecular analyses were undertaken in seven cases of CD10down GI-FL, and an identical clone was found between CD10down follicles and CD10+ BCL2+ neoplastic follicles. In the diagnosis of cases with CD10down BCL2+ follicles, careful examination with molecular studies should be carried out."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.org/dc/terms/identifier | "doi:10.1111/cas.13031"xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Maeda Y."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Okada H."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Sato Y."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Taniguchi K."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Takata K."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Takahata H."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Yanai H."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Yoshino T."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Tabata T."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Ohnishi N."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Tari A."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Omote S."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Iwamuro M."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Gion Y."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Miyata-Takata T."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Noujima-Harada M."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/author | "Nagakita K."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/name | "Cancer Sci"xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/pages | "1687-1695"xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/title | "CD10 down expression in follicular lymphoma correlates with gastrointestinal lesion involving the stomach and large intestine."xsd:string |
| http://purl.uniprot.org/citations/27513891 | http://purl.uniprot.org/core/volume | "107"xsd:string |